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If the snippet you insert requires a reference or import that you don t currently have set, Visual Studio automatically adds the reference and associated import when you insert the snippet Inserting snippets into your code is quick and easy and saves you from all that typing Using snippets can also save you time, because they provide prebuilt code for tasks that you may not perform very often

C(15) = (2:)3

I: I:

based on data collection and storage, mining the data for new hypotheses, and then accepting or rejecting the hypothesis based on data. In some cases, results are con rmed with a supplemental experiment. For example, in rational drug design, computational methods are key to de ning custom drugs instead of the more time- and labor-intensive method of manually screening thousands of samples. Computational methods won t completely replace the need for laboratory experiments with test tubes, micropipettes, mice, and other living test subjects any time soon, but they are increasingly relied upon for automating biotech research and development. More people are obtaining Ph.D.level biotech training than ever before to addresses this need. From the perspective of the computer industry, the increased activity in the computational biology is fueling database rms, hardware manufacturers, and is absorbing some of the unemployed high-tech workers displaced by the dot-com bust. Moreover, the biotech industry is positioned not only to absorb current technology, but is pushing the technology envelope, especially in the areas of databases and visualization. For example, many

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dr e-

ip r '

h(r)

For the Purchase Tracker sample application: Open the Customer class in the Code Editor Use the Define a Property code snippet to insert string properties for FirstName, Address, City, State, Zip, and Phone Add code to each Property statement to call the DataStateChanged method from the base class, as shown in the preceding chapter Use the Define a Property code snippet to add a CustomerID property The CustomerID property in the Customer class is implemented like the ProductID in the Product class:

(8.1.19)

dr e-

(8.1.20)

The integral in the Ornstein-Zernike equation of (8.1.5) is a convolution integral. Thus, in the Fourier transform domain, the integral in the OrnsteinZernike equation is proportional to the product of C(P) and H(15). Solving the equation gives (8.1.21)

6

S(p) = 1 + n o (21r)3 H(p)

biotech R&D rms have data local storage in excess of 200 tetrabytes (200,000 gigabytes). Searching, manipulating, and massaging tetrabytes of data requires high-performance hardware, powerful, new software tools, and the expertise to use them.

(8.1.22)

The closed-form solution for the direct correlation function of Percus-Yevick hard spheres is given in (8.1.14) through (8.1.18). The Fourier transform C(p) can be calculated readily and is only a function of pb, b, and 1 :

C(p) = Cpy(pb, b, 1)

Private _CustomerID As Integer Public Property CustomerID() As Integer Get Return _CustomerID End Get Private Set(ByVal value As Integer) _CustomerID = value End Set End Property

(8.1.23)

(21r)3 no Cpy (pb, b, 1)

u 2((3 + 6<5)

(8.1.24)

Given the continually decreasing cost of more powerful computers and a more interconnected biotech R&D community, along with funding from government and pharmaceutical rms, it might seem at rst glance that biotech is little more than purchasing and loading a shrink-wrapped pack age from some software vendor and conducting experiments with a mouse and keyboard To the contrary, computational methods in molecular biol ogy are far from plug and play and are fraught with challenges Many of the technologies and methodologies associated with computers and biotechnology are works in progress based on our limited understanding of molecular biology and of viability of computational approaches The future of biotechnology computing is linked to improvements in processor hardware, operating system software, and high-speed networks.

where U = pb and a, (3, <5 are given in (8.1.15) through (8.1.17). The closedform solution of H(p = 0) is obtained by letting p = 0 in (8.1.21), (8.1.23), and (8.1.24). We get

Add documentation for each property using XML comments Modify the Create method to set default values for each of the new properties You now have the majority of your Customer class

d1' [g(1') - 1] = -1

g;{];2

(8.1.25)

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